ACRV (Assured Crew Return Vehicle)
airlock
Ansari X-prize
Apollo 7
Apollo 8
Apollo 9
Apollo 10
Apollo 11
Apollo 12
Apollo 13
Apollo 14
Apollo 15
Apollo 16
Apollo 17
Apollo Project
Apollo-Soyuz Test Project
asteroid mining
Atlantis
Automated Transfer Vehicle

Bernal sphere
Big Gemini

CapCom
Challenger
Challenger disaster
Columbia
Columbus Laboratory (ISS module)
cosmonaut
crawler-transporter
CST-100

Destiny Laboratory
Discovery
docking
Dragon
Dream Chaser

Earth-orbit rendezvous
ejection capsule
Endeavour
Enterprise
escape tower
Excelsior, Project

firsts in spaceflight

Gagarin Cosmonaut Training Center
Gemini Project
Genesis inflatable module

Harmony Node 2 (ISS)
Hermes (space plane)

illicit cargo
Integrated Truss Structure
International Space Station
interstellar colonization
interstellar travel

Kibo module (Japanese Experiment Module on ISS)

Lunar Landing Research Vehicle (LLRV)
Lunar Roving Vehicle (LRV)

Manhigh, Project
Manned Maneuvering Unit (MMU)
Marquardt space sled
Manned Orbiting Laboratory (MOL)
Manned Orbiting Research Laboratory (MORL)
MASTIF (Multiple Axis Space Test Inertia Facility)
Mercury Project
Mercury Seven
Mercury Thirteen
Mir
Moon base
Multi-Purpose Crew Vehicle (MPCV)
Multi-Purpose Logistics Modules

Neutral Buoyancy Simulator

O'Neill-type colony
Orion (Crew Exploration Vehicle)

parabolic flight
Pirs Docking Compartment (ISS)
Progress

Quest Joint Airlock (ISS)

recovery (of a spacecraft)
Remote Manipulator System (RMS)
Russian manned lunar programs

Salyut
SEALAB
Shenzhou
Skylab
Soyuz
space colony
space plane
Space Shuttle
space station
space tourism
Spacehab
Spacelab
spaceport
Spaceport America
SpaceShipOne
spacesuit
spacewalk

TransHab

Vertical Assembly Building
Virgin Galactic spaceship
von Braun space station
Voskhod
Vostok

white room
Zarya Module (ISS)
Zvezda Service Module (ISS)