Myalgic encephalomyelitis (ME) is a condition defined as extreme fatigue that persists for six months or more and is not relieved by rest. Also known as chronic fatigue syndrome and post-viral fatigue syndrome, ME may be accompanied by many other non-specific symptoms, such as fever, headache, muscle and joint pains, gastric upset, dizziness, and mood changes. Often occurring after a virus infection, ME ranges in severity from chronic weariness to total physical collapse. There is no specific treatment, and recovery may take months or even years.